Testosterone induces fibrinolysis, breaking of thrombus
Testosterone induces secondary erythrocytosis.
Just like high altitude, sleep apnea and smoking.
While smoking increases fibrinogen and disrupts endothelium, leading eventually to platelets aggregation and clotting.
Men who live in Colorado, Mexico, and Tibet adjust eventually to the hypoxia as they develop higher hemoglobin.
Do they get phlebotomized for this? I doubt it.
It seems that men on testosterone react in a similar way as they become erythrocytotic.
The key factor to avoid thrombosis are thrombocytes to be kept low in number, unlike Polycythemia Vera that belongs to primary erythrocytosis and is considered a blood cancer.
For men who are on testosterone, it is common to develop Obstructive sleep apnea (OSA).
In such case when it’s treated with a CPAP mask, hematocrit drops.