Androgenic anabolic steroids (ΑΑS) may become toxic to renal metabolism, through the process of glomerular filtration in the kidneys. The first part of AAS metabolism takes place in the hepatic parenchyma (liver), but later on, chemicals have to be eliminated as waste products through urine. That takes place in glomeruli and renal tubules (proximal & distal). Kidney Damage from AAS Abuse, Supplements and Over-Training